MATLAB Fit SimBiology Model

Correct fitproblem/NLME/NCA patterns for SimBiology PK fitting; catches sbiofit pitfalls.

Tested · Works

Test report

Verdict
Tested · Works
Score
9.2/10
Tested
Jul 13, 2026
Environment
Claude Code 2.x (agent harness)
Upstream re-checked
Aug 10, 2026 · b7cda09

Compared code for a one-compartment oral-PK fit: the no-skill baseline calls sbiofit directly with a plain table and no bounds (exactly the error-prone pattern the skill's own docs warn against); the skill-guided version wraps groupedData, sets ResponseMap='Drug = Drug', adds bounds plus log-transform on ke/ka, and starts with scattersearch per the decision table.

Scored on four weighted criteria — install, triggering, output vs. baseline, docs. How scoring works

  • Installs cleanly 5/5
  • Triggers reliably 5/5
  • Output vs. baseline 8/10
  • Docs & honesty 5/5

What MATLAB Fit SimBiology Model does

Encodes the correct `fitproblem`-based workflow for SimBiology parameter estimation - groupedData wrapping, ResponseMap syntax, bounds, log-transform, error models, NLME vs sbiofit selection, virtual patients, and NCA - so an agent doesn't reach for the error-prone direct sbiofit/sbiofitmixed positional calls it explicitly warns against. Triggers on fit/estimate/calibrate/population/NCA/AUC language; explicitly excludes model construction and pure sensitivity-analysis requests, which route to sibling skills.

How to install MATLAB Fit SimBiology Model

git clone https://github.com/matlab/matlab-agentic-toolkit
cd matlab-agentic-toolkit
mkdir -p ~/.claude/skills
cp -r skills-catalog/computational-biology/matlab-fit-simbiology-model ~/.claude/skills/matlab-fit-simbiology-model

Skills live in ~/.claude/skills/ (global) or .claude/skills/ (per-project). Restart Claude Code after installing.

Commands — how to trigger MATLAB Fit SimBiology Model

  • /matlab-fit-simbiology-model Correct fitproblem/NLME/NCA patterns for SimBiology PK fitting; catches sbiofit pitfalls.

It also activates on plain-language prompts like these:

  • Help me fit this PK model in SimBiology using fitproblem correctly
  • I need to calibrate population parameters with NLME instead of sbiofit
  • Set up bounds and log-transform for this SimBiology parameter estimation

Frequently asked questions

Is the MATLAB Fit SimBiology Model skill free?
Yes. The skill itself is free from matlab/matlab-agentic-toolkit. SkillProof publishes the install command and an independent test verdict at no cost.
Does MATLAB Fit SimBiology Model work with Claude Code?
We tested it with Claude Code 2.x (agent harness) on Jul 13, 2026. Verdict: Tested · Works. Compared code for a one-compartment oral-PK fit: the no-skill baseline calls sbiofit directly with a plain table and no bounds (exactly the error-prone pattern the skill's own docs warn against); the skill-guided version wraps groupedData, sets ResponseMap='Drug = Drug', adds bounds plus log-transform on ke/ka, and starts with scattersearch per the decision table.
What is the MATLAB Fit SimBiology Model SkillProof Score?
9.2/10 — installs cleanly 5/5, triggers reliably 5/5, output vs. baseline 8/10, docs & honesty 5/5.
How do I install MATLAB Fit SimBiology Model?
Copy the install command from this page, run it in your terminal, and restart Claude Code. Skills live in ~/.claude/skills/ (global) or .claude/skills/ inside a project.
Can I use MATLAB Fit SimBiology Model with Cursor, Copilot, Gemini CLI, Codex or other AI tools?
The SKILL.md format is native to Claude (Claude Code, Desktop, claude.ai). The instructions inside adapt to other assistants: Cursor rules, GitHub Copilot instructions, Windsurf rules, Custom GPTs, AGENTS.md for OpenAI Codex, and GEMINI.md for Google Gemini CLI — our conversion guides cover each, and the free converter on the tools page does the wrapping for you.