Blast Search
Runs NCBI BLAST searches for sequence similarity/homology — needs BLAST+ or BioPython preinstalled.
Test report
- Verdict
- Tested · Didn't pass
- Tested
- Jul 14, 2026
- Environment
- Claude Code 2.x (agent harness)
- Upstream re-checked
- Aug 10, 2026 · 49dd3d8
Following the SKILL.md literally hits a wall immediately: blastn isn't installed and there's no fallback guidance, while a plain five-line Python script found the same 95% sequence identity in under a second.
Scored on four weighted criteria — install, triggering, output vs. baseline, docs. How scoring works
- Installs cleanly 5/5
- Triggers reliably 5/5
- Output vs. baseline 2/10
- Docs & honesty 2/5
What Blast Search does
Runs local (blastn/blastp/blastx/tblastn) or remote NCBI BLAST+ searches to find similar DNA, RNA, or protein sequences and identify genes by homology, presenting hits as a ranked table with identity and E-values. Triggers on requests to BLAST a sequence, find similar sequences, or run a homology search. The instructions assume a preconfigured bioinformatics container with BLAST+ and BioPython already installed, and give no fallback when those binaries are missing.
How to install Blast Search
git clone https://github.com/BioTender-max/awesome-bio-agent-skills
cd awesome-bio-agent-skills
mkdir -p ~/.claude/skills
cp -r skills/bioclaw/blast-search ~/.claude/skills/blast-search
Skills live in ~/.claude/skills/ (global) or .claude/skills/
(per-project). Restart Claude Code after installing.
Commands — how to trigger Blast Search
-
/blast-searchRuns NCBI BLAST searches for sequence similarity/homology — needs BLAST+ or BioPython preinstalled.
It also activates on plain-language prompts like these:
-
Can you BLAST this DNA sequence against the nt database for me? -
I need to find genes similar to this protein sequence via homology. -
Run a local blastp search comparing these two protein sequences.
Frequently asked questions
- Is the Blast Search skill free?
- Yes. The skill itself is free from BioTender-max/awesome-bio-agent-skills. SkillProof publishes the install command and an independent test verdict at no cost.
- Does Blast Search work with Claude Code?
- We tested it with Claude Code 2.x (agent harness) on Jul 14, 2026. Verdict: Tested · Didn't pass. Following the SKILL.md literally hits a wall immediately: blastn isn't installed and there's no fallback guidance, while a plain five-line Python script found the same 95% sequence identity in under a second.
- How do I install Blast Search?
- Copy the install command from this page, run it in your terminal, and restart Claude Code. Skills live in ~/.claude/skills/ (global) or .claude/skills/ inside a project.
- Can I use Blast Search with Cursor, Copilot, Gemini CLI, Codex or other AI tools?
- The SKILL.md format is native to Claude (Claude Code, Desktop, claude.ai). The instructions inside adapt to other assistants: Cursor rules, GitHub Copilot instructions, Windsurf rules, Custom GPTs, AGENTS.md for OpenAI Codex, and GEMINI.md for Google Gemini CLI — our conversion guides cover each, and the free converter on the tools page does the wrapping for you.